Description

Tetramethylammonium Hydroxide (CAS NO 75-59-2) is a highly versatile and powerful organic base, widely recognized for its exceptional solubility in water and polar organic solvents. This quaternary ammonium compound is a critical reagent in advanced technology manufacturing and analytical chemistry, where its strong alkalinity and ionic nature provide unique advantages over inorganic bases. It is an essential material for electronics manufacturers, pharmaceutical developers, and research laboratories requiring precise, metal-ion-free alkaline conditions.

Application

• Semiconductor & Microelectronics: As a key component in tetramethylammonium hydroxide (TMAH) photoresist developers for silicon wafer patterning in integrated circuit (IC) fabrication.
• Analytical Chemistry: Used as a mobile phase modifier in HPLC and ion chromatography to improve peak shape and separation of acidic compounds.
• Organic Synthesis & Catalysis: Employed as a non-nucleophilic strong base for deprotonation reactions, ester hydrolysis, and as a phase-transfer catalyst.
• Chemical Research: Serves as a template agent or structure-directing agent (SDA) in the synthesis of zeolites and other microporous materials.
• Surfactant & Dispersant: Utilized in specialized formulations where its cationic properties are beneficial for surface modification and nanoparticle dispersion.
• Biochemistry & Pharmaceuticals: Acts as an alkaline agent in buffer systems and in the purification or modification of biomolecules.

Basic Information

Product Name	Tetramethylammonium Hydroxide
CAS No.	75-59-2
Molecular Formula	C₄H₁₃NO
Molecular Weight	91.15 g/mol
Synonyms	TMAH; Tetramethylammonium hydroxide solution; N,N,N-Trimethylmethanaminium hydroxide; Methanaminium, N,N,N-trimethyl-, hydroxide; TMA-OH; Tetramethylazanium hydroxide
EINECS	200-882-9

Quality Control

Our Tetramethylammonium Hydroxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets precise specifications for purity, concentration, and metal ion content, which is critical for sensitive applications like semiconductor manufacturing. A Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area. This product is hygroscopic (moisture-sensitive) and a strong alkali. It should be kept away from acids and incompatible materials. For aqueous solutions, standard room temperature (15-25°C) storage is typical; refer to the specific product label or SDS for detailed instructions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (TMAH)	≥ 25.0% in water (or as specified)
Purity (HPLC)	≥ 99.0%
Chloride (Cl)	≤ 50 ppm
Sulfate (SO₄)	≤ 50 ppm
Heavy Metals (as Pb)	≤ 10 ppm
Iron (Fe)	≤ 5 ppm
Potassium (K)	≤ 5 ppm
Sodium (Na)	≤ 5 ppm
pH	> 13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.