Description

1-Methyl-3-Nitro-1-Nitrosoguanidine is a specialized nitrosated guanidine derivative primarily used as a potent alkylating agent and mutagen in biochemical research. This compound is critical for inducing controlled genetic mutations in laboratory settings, enabling studies in molecular biology, genetics, and carcinogenesis. It is an essential reagent for researchers and institutions in the life sciences, pharmaceutical development, and agricultural biotechnology sectors.

Application

• Biochemical Research: As a powerful mutagen for inducing point mutations in bacterial and eukaryotic cell cultures.
• Molecular Biology: Used in studies of DNA damage, repair mechanisms, and the genetic basis of diseases.
• Pharmaceutical Development: Employed in mutagenicity testing and screening programs during drug discovery and safety assessment.
• Agricultural Biotechnology: Utilized for creating genetic variation in plant breeding and crop improvement research.
• Carcinogenesis Research: Serves as a model alkylating agent in studies investigating the mechanisms of chemical carcinogens.
• Microbiology: Applied in microbial genetics for strain development and functional genomics.

Basic Information

Product Name	1-Methyl-3-Nitro-1-Nitrosoguanidine
CAS No.	70-25-7
Molecular Formula	C₂H₅N₅O₃
Molecular Weight	147.09 g/mol
Synonyms	MNNG; N-Methyl-N'-nitro-N-nitrosoguanidine; Nitrosomethylnitroguanidine; 1-Methyl-1-nitroso-3-nitroguanidine; NSC 9369; Nitroso-methylguanidine; MNNG mutagen; Guanine, 1-methyl-3-nitro-1-nitroso-
EINECS	200-730-1

Quality Control

Our 1-Methyl-3-Nitro-1-Nitrosoguanidine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is characterized by comprehensive analytical techniques including HPLC, NMR, and FTIR. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 124 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.