Description

7-Azabicyclo[2.2.1]Heptane,2-(5-Pyrimidinyl)-,(1R,2R,4S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic amine derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique bridged structure and pyrimidine substituent make it a valuable scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific stereochemistry is required for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of novel, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is crucial for efficacy.
• Ligand & Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme interactions and biological pathways due to its rigid, three-dimensional structure.
• Material Science Research: Investigated as a monomer or building block for creating novel polymers with specific mechanical or optical properties.

Basic Information

Product Name	7-Azabicyclo[2.2.1]Heptane,2-(5-Pyrimidinyl)-,(1R,2R,4S)-Rel-(9Ci)
CAS No.	699022-20-3
Molecular Formula	C10H13N3
Molecular Weight	175.23 g/mol
Synonyms	(1R,2R,4S)-2-(Pyrimidin-5-yl)-7-azabicyclo[2.2.1]heptane; rel-(1R,2R,4S)-2-(Pyrimidin-5-yl)-7-azabicyclo[2.2.1]heptane; 5-((1R,2R,4S)-7-Azabicyclo[2.2.1]heptan-2-yl)pyrimidine; 2-(5-Pyrimidinyl)-7-azabicyclo[2.2.1]heptane, (1R,2R,4S)-rel-; Bicyclo[2.2.1]heptane, 2-(5-pyrimidinyl)-7-aza-, (1R,2R,4S)-rel-
EINECS	Contact for details

Quality Control

Our 7-Azabicyclo[2.2.1]Heptane,2-(5-Pyrimidinyl)-,(1R,2R,4S)-Rel-(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and mass spectrometry for structural confirmation, to ensure it meets the exacting standards required for research and process development. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.