Description

7-Fluoro-5-Nitro-2,3-Dihydrobenzo[B][1,4]Dioxine is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzo[1,4]dioxine scaffold substituted with fluorine and nitro groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for drug discovery programs, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in organic synthesis as a versatile scaffold for further functionalization via reactions targeting the nitro group or the aromatic ring system.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	7-Fluoro-5-Nitro-2,3-Dihydrobenzo[B][1,4]Dioxine
CAS No.	698985-51-2
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	7-Fluoro-5-nitro-2,3-dihydro-1,4-benzodioxine; 5-Nitro-7-fluoro-2,3-dihydro-1,4-benzodioxine; 2,3-Dihydro-7-fluoro-5-nitro-1,4-benzodioxine; 7-Fluoro-5-nitro-2,3-dihydrobenzo-1,4-dioxine; 698985-51-2; 7-Fluoro-5-nitrobenzo[1,4]dioxane; 5-Nitro-7-fluorobenzo[b][1,4]dioxine
EINECS	Contact for details

Quality Control

Our 7-Fluoro-5-Nitro-2,3-Dihydrobenzo[B][1,4]Dioxine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.