Description

6-Bromo-5,7-Dimethyl-1,2,3,4-Tetrahydro-1,8-Naphthyridine is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated naphthyridine core structure. This compound is of significant value for its role as a critical building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable bromo substituent.
• Process Chemistry Development: Employed in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and methodology development.

Basic Information

Product Name	6-Bromo-5,7-Dimethyl-1,2,3,4-Tetrahydro-1,8-Naphthyridine
CAS No.	698974-42-4
Molecular Formula	C11H15BrN2
Molecular Weight	255.16 g/mol
Synonyms	6-Bromo-5,7-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine; 1,2,3,4-Tetrahydro-6-bromo-5,7-dimethyl-1,8-naphthyridine; 698974-42-4; 6-Bromo-5,7-dimethyl-1,2,3,4-tetrahydro-[1,8]naphthyridine; 6-Bromo-5,7-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine (CAS 698974-42-4)
EINECS	Contact for details

Quality Control

Our 6-Bromo-5,7-Dimethyl-1,2,3,4-Tetrahydro-1,8-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.