Description

(S)-Ethyl 7-Fluoro-1-(1-Hydroxy-3-Methylbutan-2-Yl)-6-Iodo-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex chiral quinoline structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly due to its functionalized scaffold which serves as a key building block. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel fluoroquinolone-based antibiotics and other active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs targeting bacterial infections.
• Process Development: Serves as a key intermediate in the scale-up and process chemistry development for new drug candidates.
• Academic Research: Employed in university and institutional labs for studying synthetic methodologies and the biological activity of complex heterocyclic compounds.
• Custom Synthesis: A starting material for the custom synthesis of more complex, target-specific molecules for preclinical evaluation.

Basic Information

Product Name	(S)-Ethyl 7-Fluoro-1-(1-Hydroxy-3-Methylbutan-2-Yl)-6-Iodo-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate
CAS No.	697762-60-0
Molecular Formula	C18H21FINO4
Molecular Weight	477.17 g/mol
Synonyms	(S)-Ethyl 7-Fluoro-1-(1-hydroxy-3-methylbutan-2-yl)-6-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1,4-Dihydro-7-fluoro-1-[(1S)-1-hydroxy-3-methyl-2-butyl]-6-iodo-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Ethyl (S)-7-fluoro-1-(1-hydroxy-3-methylbutan-2-yl)-6-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate; 697762-60-0; (S)-7-Fluoro-1-(1-hydroxy-3-methyl-2-butyl)-6-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 7-Fluoro-1-(1-Hydroxy-3-Methylbutan-2-Yl)-6-Iodo-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.