Description

Carbamic Acid, [(1S,3R)-1-Ethynyl-3-Hydroxybutyl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and antiviral research.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts.
• Peptidomimetics & PROTACs: Employed in the construction of peptide analogs and Proteolysis Targeting Chimeras (PROTACs) for drug discovery.
• Material Science: Potential monomer or cross-linker for specialty polymers with tailored properties.
• Academic & Institutional R&D: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Carbamic Acid, [(1S,3R)-1-Ethynyl-3-Hydroxybutyl]-, 1,1-Dimethylethyl Ester
CAS No.	697752-33-3
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	(1S,3R)-1-Ethynyl-3-hydroxybutyl carbamate tert-butyl ester; tert-Butyl N-[(1S,3R)-1-ethynyl-3-hydroxybutyl]carbamate; (3R,5S)-5-Ethynyl-3-hydroxytetrahydro-2H-pyran-2-one tert-butyl carbamate (tautomeric form); Boc-protected ethynyl hydroxybutyl amine; Chiral Boc-amino alcohol alkyne; (S,R)-Ethynylhydroxybutyl tert-butylcarbamate; CAS 697752-33-3
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1S,3R)-1-Ethynyl-3-Hydroxybutyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.