Description

8-Bromo-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a versatile, brominated scaffold that enables precise molecular modifications for developing novel active compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone-based antibiotics and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bioactive quinoline core.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine substituent.
• Material Science Research: Serves as a starting material for creating organic ligands and functionalized molecules for advanced materials.
• Academic & R&D Laboratories: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	8-Bromo-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	692764-07-1
Molecular Formula	C₁₂H₁₀BrNO₃
Molecular Weight	296.12 g/mol
Synonyms	Ethyl 8-Bromo-4-oxo-1,4-dihydroquinoline-3-carboxylate; 8-Bromo-4-hydroxyquinoline-3-carboxylic acid ethyl ester; 8-Bromoquinoline-3-carboxylic acid ethyl ester, 4-oxo-1,4-dihydro-; 1,4-Dihydro-8-bromo-4-oxoquinoline-3-carboxylic Acid Ethyl Ester; 692764-07-1; Ethyl 8-bromo-1,4-dihydro-4-oxoquinoline-3-carboxylate; 8-Bromo-4-oxo-1H-quinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.