Description

8-(1,3,4-Oxadiazol-2-Yl)-2,4-Bis(Trifluoromethyl)Imidazo[1,2-A][1,8]Naphthyridine is a high-value, complex heterocyclic compound featuring a fused imidazo[1,2-a][1,8]naphthyridine core functionalized with trifluoromethyl groups and an oxadiazole moiety. This unique molecular architecture makes it a critical advanced intermediate for pharmaceutical and agrochemical research, particularly in the development of novel active ingredients. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating new chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology, antiviral, and anti-inflammatory research pipelines.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the oxadiazole and trifluoromethyl groups.
• Material Science Precursor: Serves as a sophisticated organic ligand or core structure for developing functional materials, such as organic semiconductors or fluorescent dyes.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions due to its complex, drug-like structure.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material (CTM) or commercial Active Pharmaceutical Ingredient (API) manufacturing.

Basic Information

Item	Details
Product Name	8-(1,3,4-Oxadiazol-2-Yl)-2,4-Bis(Trifluoromethyl)Imidazo[1,2-A][1,8]Naphthyridine
CAS No.	691868-88-9
Molecular Formula	C15H5F6N5O
Molecular Weight	385.22 g/mol
Synonyms	8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine; Imidazo[1,2-a][1,8]naphthyridine, 8-(1,3,4-oxadiazol-2-yl)-2,4-bis(trifluoromethyl)-; 2,4-Bis(trifluoromethyl)-8-(1,3,4-oxadiazol-2-yl)imidazo[1,2-a][1,8]naphthyridine; 691868-88-9; SCHEMBL21806227; AKOS040759623; ZINC000257830511; AOB81117
EINECS	Contact for details

Quality Control

Our 8-(1,3,4-Oxadiazol-2-Yl)-2,4-Bis(Trifluoromethyl)Imidazo[1,2-A][1,8]Naphthyridine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.