Description

tert-Butyl 4-(2-Aminophenoxy)Tetrahydro-1(2H)-Pyridinecarboxylate is a high-value, advanced pharmaceutical intermediate characterized by its unique molecular scaffold. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and cardiovascular disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates and complex APIs.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing nitrogen- and oxygen-containing heterocyclic frameworks.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Precursor for Ligand Synthesis: Utilized in the development of specialized ligands for catalysis and medicinal chemistry applications.

Basic Information

Product Name	tert-Butyl 4-(2-Aminophenoxy)Tetrahydro-1(2H)-Pyridinecarboxylate
CAS No.	690632-14-5
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	1,2,3,6-Tetrahydro-4-[(2-aminophenoxy)methyl]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(2-aminophenoxy)methyl]-1,2,3,6-tetrahydropyridine-1-carboxylate; 4-(2-Aminophenoxymethyl)-1-tert-butoxycarbonyl-1,2,3,6-tetrahydropyridine; 1-Boc-4-[(2-aminophenoxy)methyl]-1,2,3,6-tetrahydropyridine; tert-Butyl 4-(2-aminophenoxymethyl)-3,6-dihydro-2H-pyridine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Aminophenoxy)Tetrahydro-1(2H)-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting full specifications are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.