Description

1,2-Cyclobutanediamine,N,N,n-Trimethyl-,(1R,2R)-Rel-(9Ci) is a high-purity, chiral diamine derivative featuring a constrained cyclobutane ring system. This compound is a critical chiral building block and ligand for asymmetric synthesis, offering precise stereochemical control in the creation of complex molecules. It is essential for research and development in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Catalysis: Serves as a chiral ligand or catalyst precursor in transition metal-catalyzed reactions, such as hydrogenation and C-C bond formation.
• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and medicinal chemistry research.
• Ligand Library Development: Used to create and screen libraries of chiral ligands for catalyst discovery and optimization.

Basic Information

Product Name	1,2-Cyclobutanediamine,N,N,n-Trimethyl-,(1R,2R)-Rel-(9Ci)
CAS No.	689208-45-5
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(1R,2R)-N,N,N'-Trimethyl-1,2-cyclobutanediamine; (1R,2R)-N,N,N'-Trimethylcyclobutane-1,2-diamine; (1R,2R)-1,2-Bis(methylamino)cyclobutane; rel-(1R,2R)-N,N,N'-Trimethyl-1,2-cyclobutanediamine; (1R,2R)-TMCDA; Chiral TMCDA; N,N,N'-Trimethyl-(1R,2R)-cyclobutane-1,2-diamine
EINECS	Contact for details

Quality Control

Our 1,2-Cyclobutanediamine,N,N,n-Trimethyl-,(1R,2R)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.