Description

Dispiro[1,3-Dioxolane-2,1(4H)-Pentalene-4,2-Oxirane], Hexahydro-, (2R,3As,6As)- (9Ci) is a complex, stereochemically defined spirocyclic compound that serves as a versatile and high-value synthetic intermediate. Its unique fused ring system containing dioxolane and oxirane (epoxide) functional groups makes it a critical building block for constructing sophisticated molecular architectures with precise three-dimensional control. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in asymmetric synthesis, medicinal chemistry, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Utilized as a chiral scaffold or epoxide donor in stereoselective reactions to introduce multiple stereocenters with high enantiomeric excess.
• Medicinal Chemistry & Drug Discovery: Employed in lead optimization and library synthesis to explore novel chemical space and develop compounds with improved pharmacokinetic properties.
• Advanced Material Synthesis: Serves as a monomer or cross-linking agent for developing specialty polymers, resins, or coatings with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Used as a backbone for constructing novel chiral ligands and organocatalysts for use in homogeneous catalysis.
• Academic and Industrial R&D: A valuable tool for methodological development in organic synthesis and for probing new reaction pathways.

Basic Information

Product Name	Dispiro[1,3-Dioxolane-2,1(4H)-Pentalene-4,2-Oxirane], Hexahydro-, (2R,3As,6As)- (9Ci)
CAS No.	688359-69-5
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	Hexahydrodispiro[1,3-dioxolane-2,1'(4'H)-pentalene-4',2''-oxirane], (2R,3aS,6aS)-rel-; (2R,3aS,6aS)-Hexahydrodispiro[1,3-dioxolane-2,1'(4'H)-pentalene-4',2''-oxirane]; (2R,3aS,6aS)-Dispiro[1,3-dioxolane-2,1(4H)-pentalene-4,2-oxirane], hexahydro-; Chiral Spirocyclic Dioxolane-Oxirane; (2R,3aS,6aS)-Hexahydro-2H-dispiro[1,3-dioxolane-2,1'-pentalene-4',2''-oxirane].
EINECS	Contact for details

Quality Control

Our Dispiro[1,3-Dioxolane-2,1(4H)-Pentalene-4,2-Oxirane], Hexahydro-, (2R,3As,6As)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and GC/MS, to ensure high chemical and enantiomeric purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.