Description

3,4-Pyrrolidinediol,2-(Hydroxymethyl)-4-Methyl-,(2R,3S,4S)-(9Ci) is a high-purity, stereochemically defined pyrrolidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique polyhydroxylated structure makes it a valuable intermediate for constructing complex molecules with precise three-dimensional orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral catalysts, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and neurological therapeutic areas.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and glycomimetics due to its carbohydrate-like scaffold.
• Fine Chemical Synthesis: A versatile building block for creating complex natural product analogs and specialty chemicals with high added value.
• Agrochemical Development: Potential intermediate in the research and development of new, targeted agrochemicals with specific modes of action.

Basic Information

Product Name	3,4-Pyrrolidinediol,2-(Hydroxymethyl)-4-Methyl-,(2R,3S,4S)-(9Ci)
CAS No.	686708-45-2
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2R,3S,4S)-2-(Hydroxymethyl)-4-methylpyrrolidine-3,4-diol; (2R,3S,4S)-4-Methyl-2-(hydroxymethyl)pyrrolidine-3,4-diol; 2-(Hydroxymethyl)-4-methyl-3,4-pyrrolidinediol (2R,3S,4S)-; 686708-45-2; Polyhydroxylated Pyrrolidine Derivative; Chiral Pyrrolidinetriol
EINECS	Contact for details

Quality Control

Our 3,4-Pyrrolidinediol,2-(Hydroxymethyl)-4-Methyl-,(2R,3S,4S)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We support development and commercial projects with material that meets stringent pharmaceutical-grade standards, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.