Description

2-(1,4-Dioxa-8-Aza-Spiro[4.5]Dec-8-Yl)-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. Its complex spirocyclic and fused pyridopyrimidine structure makes it a valuable intermediate for constructing novel molecular architectures with potential biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new pesticides or herbicides with novel modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function or biological pathways.
• Advanced Material Synthesis: Potential intermediate for creating specialty chemicals or functional materials with specific electronic or photophysical properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.

Basic Information

Product Name	2-(1,4-Dioxa-8-Aza-Spiro[4.5]Dec-8-Yl)-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde
CAS No.	686300-74-3
Molecular Formula	C₁₆H₁₇N₃O₄
Molecular Weight	315.33 g/mol
Synonyms	2-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxaldehyde; 4H-Pyrido[1,2-a]pyrimidine-3-carboxaldehyde, 2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-4-oxo-; 686300-74-3; 2-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde; Spirocyclic pyridopyrimidine carbaldehyde; Ketal-protected amino aldehyde intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to maximize shelf life and stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.