Description

1-Formyl-2-Methyl-Indolizine-3-Carbonitrile is a versatile and high-value heterocyclic building block used in advanced organic synthesis. Its unique indolizine scaffold, functionalized with formyl and nitrile groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex indolizine-based libraries and exploring new chemical spaces.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the indolizine structure contributes to color and stability properties.

Basic Information

Product Name	1-Formyl-2-Methyl-Indolizine-3-Carbonitrile
CAS No.	685891-12-7
Molecular Formula	C11H8N2O
Molecular Weight	184.20 g/mol
Synonyms	2-Methyl-1-formylindolizine-3-carbonitrile; 3-Cyano-2-methylindolizine-1-carboxaldehyde; 1-Formyl-2-methylindolizine-3-carbonitrile; 2-Methylindolizine-1,3-dicarbonitrile-1-carboxaldehyde; Indolizine-3-carbonitrile, 1-formyl-2-methyl-; 685891-12-7; 1-Cyano-2-methyl-3-formylindolizine
EINECS	Contact for details

Quality Control

Our 1-Formyl-2-Methyl-Indolizine-3-Carbonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; prolonged exposure to air should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.