Description

1-Quinazolin-4-Yl-Piperidine-4-Carboxylic Acid CAS NO 685862-10-6 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for conjugation to carriers, labels, or other molecules to create research tools and diagnostic probes.
• Chemical Library Synthesis: A valuable scaffold for constructing diverse compound libraries used in high-throughput screening (HTS) campaigns.
• Academic & Contract Research: Employed in university and CRO settings for fundamental research into heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	1-Quinazolin-4-Yl-Piperidine-4-Carboxylic Acid
CAS No.	685862-10-6
Molecular Formula	C15H15N3O2
Molecular Weight	269.30 g/mol
Synonyms	4-(Piperidine-4-carboxylic acid)quinazoline; 4-(4-Carboxypiperidin-1-yl)quinazoline; 1-(Quinazolin-4-yl)piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid, 1-quinazolin-4-yl-; Quinazolin-4-yl-piperidine-4-carboxylic acid; 685862-10-6; UNII-9V6C6687ST
EINECS	Contact for details

Quality Control

Our production of 1-Quinazolin-4-Yl-Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.