Description

4H-Quinolizin-4-One,9-Ethyloctahydro-6-(Hydroxymethyl)-,(6S,9R,9As)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering researchers and manufacturers precise control over the final product's stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in developing new therapeutic agents, particularly within medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of novel drug candidates, especially those targeting the central nervous system or infectious diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic value.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production for active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Used in university and institutional labs for studies in organic synthesis, heterocyclic chemistry, and pharmacology.

Basic Information

Product Name	4H-Quinolizin-4-One,9-Ethyloctahydro-6-(Hydroxymethyl)-,(6S,9R,9As)-(9Ci)
CAS No.	685138-88-9
Molecular Formula	C14H23NO2
Molecular Weight	237.34 g/mol
Synonyms	(6S,9R,9aS)-9-Ethyloctahydro-6-(hydroxymethyl)-4H-quinolizin-4-one; 9-Ethyloctahydro-6-(hydroxymethyl)-4H-quinolizin-4-one (6S,9R,9aS)-; (6S,9R,9aS)-9-Ethyl-6-(hydroxymethyl)octahydro-4H-quinolizin-4-one; Octahydro-6-(hydroxymethyl)-9-ethyl-4H-quinolizin-4-one, (6S,9R,9aS)-; A stereoisomer of a quinolizidine alkaloid precursor. Contact for additional trade names or abbreviations.
EINECS	Contact for details

Quality Control

Our 4H-Quinolizin-4-One,9-Ethyloctahydro-6-(Hydroxymethyl)-,(6S,9R,9As)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.