Description

4H-Cyclopent[C]Inden-4-One,Decahydro-3-Methyl-,(3R,3Ar,5As,9Ar)-Rel-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex polycyclic structure, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D. The product, CAS NO 685109-83-5, is supplied under stringent quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Exploits its defined stereocenters for the construction of other enantiomerically pure molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a high degree of structural complexity and purity.

Basic Information

Product Name	4H-Cyclopent[C]Inden-4-One,Decahydro-3-Methyl-,(3R,3Ar,5As,9Ar)-Rel-(9Ci)
CAS No.	685109-83-5
Molecular Formula	C13H20O
Molecular Weight	192.30 g/mol
Synonyms	(3R,3aR,5aS,9aR)-Decahydro-3-methyl-4H-cyclopent[c]inden-4-one; rel-(3R,3aR,5aS,9aR)-Decahydro-3-methyl-4H-cyclopent[c]inden-4-one; 4H-Cyclopent[c]inden-4-one, decahydro-3-methyl-, (3R,3aR,5aS,9aR)-rel-; Decahydro-3-methyl-4H-cyclopent[c]inden-4-one (rel-(3R,3aR,5aS,9aR)-isomer); 685109-83-5; Advanced Pharmaceutical Intermediate 685109-83-5; Chiral Polycyclic Ketone Intermediate.
EINECS	Contact for details

Quality Control

Our 4H-Cyclopent[C]Inden-4-One,Decahydro-3-Methyl-,(3R,3Ar,5As,9Ar)-Rel-(9Ci) is produced and tested under a rigorous quality management system. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects with consistent quality that meets the stringent requirements of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.