Description

Methyl 3-Iodobenzo[B]Thiophene-2-Carboxylate is a high-purity, functionalized benzothiophene derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of iodine and ester functional groups, enabling versatile cross-coupling reactions and further molecular elaboration. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold's bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for organic electronic materials, such as semiconductors for OLEDs or organic photovoltaics.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Synthesis: Versatile intermediate for further functional group transformations, including hydrolysis to the carboxylic acid or reduction to the alcohol.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis or as a core structure in catalyst design.

Basic Information

Product Name	Methyl 3-Iodobenzo[B]Thiophene-2-Carboxylate
CAS No.	683274-54-6
Molecular Formula	C10H7IO2S
Molecular Weight	318.13 g/mol
Synonyms	Methyl 3-iodobenzo[b]thiophene-2-carboxylate; 3-Iodobenzo[b]thiophene-2-carboxylic acid methyl ester; Benzo[b]thiophene-2-carboxylic acid, 3-iodo-, methyl ester; Methyl 3-iodo-1-benzothiophene-2-carboxylate; 2-Methoxycarbonyl-3-iodobenzo[b]thiophene; 683274-54-6
EINECS	Contact for details

Quality Control

Our Methyl 3-Iodobenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, guaranteeing it meets the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.