Description

3-Bromo-4-Chloro-2-(Trifluoromethyl)Quinoline is a high-purity, multi-functional halogenated quinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring bromine, chlorine, and trifluoromethyl substituents, makes it an exceptionally valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for drug discovery programs, particularly in developing kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides, herbicides, and fungicides, where the halogen and fluorine atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Catalyst & Ligand Development: Utilized as a starting material for synthesizing novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to custom synthesis organizations (CSOs) and CDMOs for client-specific projects requiring this specialized quinoline scaffold.

Basic Information

Product Name	3-Bromo-4-Chloro-2-(Trifluoromethyl)Quinoline
CAS No.	683274-52-4
Molecular Formula	C₁₀H₄BrClF₃N
Molecular Weight	310.50 g/mol
Synonyms	3-Bromo-4-chloro-2-(trifluoromethyl)quinoline; Quinoline, 3-bromo-4-chloro-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-3-bromo-4-chloroquinoline; 4-Chloro-3-bromo-2-trifluoromethylquinoline; 3-Bromo-4-chloro-2-trifluoromethylquinoline; BCTQ (common abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Chloro-2-(Trifluoromethyl)Quinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.