Description

4-Bromo-5-(Trifluoromethyl)-2-Nitrobenzenamine is a high-purity, multi-functional aromatic amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromo, trifluoromethyl, and nitro substituents on an aniline core, makes it a versatile precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Serves as a crucial building block in the design and synthesis of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and nitro groups.
• Material Science Precursor: Used in the development of advanced organic electronic materials, such as dyes, pigments, and charge-transport molecules, due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to construct more complex biaryl structures.
• Functional Group Transformation: The nitro group can be selectively reduced to an amine, enabling further derivatization and the creation of diverse chemical libraries for screening.

Basic Information

Product Name	4-Bromo-5-(Trifluoromethyl)-2-Nitrobenzenamine
CAS No.	683241-86-3
Molecular Formula	C7H4BrF3N2O2
Molecular Weight	285.02 g/mol
Synonyms	2-Nitro-4-bromo-5-(trifluoromethyl)aniline; 4-Bromo-5-(trifluoromethyl)-2-nitroaniline; 2-Amino-4-bromo-5-(trifluoromethyl)nitrobenzene; 4-Bromo-α,α,α-trifluoro-5-nitro-o-toluidine; Benzenamine, 4-bromo-5-(trifluoromethyl)-2-nitro-; AN-768/43404057
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-(Trifluoromethyl)-2-Nitrobenzenamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.