Description

3-(Boc-Amino)-4-(4-Fluorophenyl)Butyric Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the combination of the Boc-protected amine group and the fluorinated aromatic side chain, which are essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for peptide mimetics and small molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to incorporate fluorinated phenylalanine analogs into peptide chains to enhance metabolic stability and binding affinity.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors targeting specific enzymatic pathways.
• Chemical Biology & Probe Synthesis: Utilized in creating labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom synthesis projects requiring fluorinated, protected amino acid structures.
• Academic Research: Employed in university and institutional labs for methodological development in asymmetric synthesis and fluorine chemistry.

Basic Information

Product Name	3-(Boc-Amino)-4-(4-Fluorophenyl)Butyric Acid
CAS No.	683219-73-0
Molecular Formula	C15H20FNO4
Molecular Weight	297.32 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-4-(4-fluorophenyl)butanoic acid; N-Boc-4-(4-Fluorophenyl)-β-homoalanine; Boc-4-(4-Fluorophenyl)-D,L-homoalanine; 4-(4-Fluorophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid; (RS)-3-(tert-Butoxycarbonylamino)-4-(4-fluorophenyl)butyric acid; N-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)-β-homoalanine; Butanoic acid, 3-[(1,1-dimethylethoxy)carbonyl]amino]-4-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 3-(Boc-Amino)-4-(4-Fluorophenyl)Butyric Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.