Description

3-Amino-3-(2-Hydroxy-4-Methoxy-Phenyl)-Propionic Acid is a specialized aromatic amino acid derivative that serves as a high-value building block in advanced organic synthesis. Its unique structure, featuring both amino and carboxylic acid functional groups on a substituted phenyl ring, makes it a critical intermediate for creating complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and sophisticated chemical probes.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetic Chemistry: Used to incorporate unnatural amino acid residues into peptide analogs to enhance stability, bioavailability, and receptor binding affinity.
• Ligand Synthesis: Serves as a precursor for chelating agents and complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Bioconjugation: The carboxylic acid and amino groups enable its use as a linker molecule for attaching fluorescent dyes, drugs, or other payloads to biomolecules.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Fine Chemical Synthesis: A versatile intermediate for creating specialty chemicals used in agrochemicals, dyes, and advanced materials.

Basic Information

Product Name	3-Amino-3-(2-Hydroxy-4-Methoxy-Phenyl)-Propionic Acid
CAS No.	682803-94-7
Molecular Formula	C10H13NO4
Molecular Weight	211.22 g/mol
Synonyms	3-Amino-3-(2-hydroxy-4-methoxyphenyl)propanoic acid; 2-Hydroxy-4-methoxy-β-aminohydrocinnamic acid; β-Amino-β-(2-hydroxy-4-methoxyphenyl)propionic acid; (3R/S)-3-Amino-3-(2-hydroxy-4-methoxyphenyl)propanoic acid; 3-Amino-3-(2-hydroxy-4-methoxyphenyl)propionic acid; DL-3-Amino-3-(2-hydroxy-4-methoxyphenyl)propionic acid; 682803-94-7
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(2-Hydroxy-4-Methoxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.