Description

4H-Cyclopenta-1,3-Dioxol-4-Ol, 3A,6A-Dihydro-2,2-Dimethyl-4-[(Triphenylmethoxy)Methyl]-, (3As,4S,6As)- is a sophisticated chiral intermediate of significant importance in advanced organic synthesis. This compound matters because its unique protected diol and trityl ether functionalities make it a versatile building block for constructing complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), nucleoside analogs, and other fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the multi-step synthesis of novel drug candidates and complex bioactive molecules.
• Nucleoside & Nucleotide Chemistry: Serves as a protected sugar or backbone component for the synthesis of modified nucleosides and oligonucleotides.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to introduce specific stereocenters.
• Protecting Group Strategy: The triphenylmethoxy (trityl) group provides a robust protecting group for primary alcohols in complex synthetic sequences.
• Academic & Process R&D: Used in research laboratories for method development and scaling up synthetic routes for high-value compounds.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals requiring high purity and defined stereochemistry.

Basic Information

Product Name	4H-Cyclopenta-1,3-Dioxol-4-Ol, 3A,6A-Dihydro-2,2-Dimethyl-4-[(Triphenylmethoxy)Methyl]-, (3As,4S,6As)-
CAS No.	681854-00-2
Molecular Formula	C26H26O4
Molecular Weight	402.48 g/mol
Synonyms	(3aS,4S,6aS)-3a,6a-Dihydro-2,2-dimethyl-4-[(triphenylmethoxy)methyl]-4H-cyclopenta-1,3-dioxol-4-ol; (4S)-4-[(Trityloxy)methyl]-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde acetal derivative; 1,2-O-Isopropylidene-4-O-trityl-D-erythro-pent-1-en-3-ulose cyclic acetal; Protected D-ribose derivative; Trityl ether of a protected pentose; Chiral acetonide trityl ether intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, NMR, and mass spectrometry to confirm identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.