Description

1-Benzyl-Piperidine-4-Carboxylic Acid Hydrochloride is a high-purity organic salt derivative of piperidine-4-carboxylic acid, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a protected, salt-stabilized form of the carboxylic acid functional group, which is essential for precise molecular construction. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and complex specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used as a precursor in the creation of advanced pesticides and herbicides requiring specific piperidine-based architectures.
• Ligand and Catalyst Development: Serves as a starting material for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and conformationally restricted biomolecules.
• Academic & Industrial R&D: A valuable reagent for methodological chemistry research and process development in fine chemical production.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	1-Benzyl-Piperidine-4-Carboxylic Acid Hydrochloride
CAS No.	681482-53-1
Molecular Formula	C14H19NO2 • HCl
Molecular Weight	269.77 g/mol (Free base: 233.31 g/mol)
Synonyms	1-Benzylpiperidine-4-carboxylic acid hydrochloride; 4-Piperidinecarboxylic acid, 1-(phenylmethyl)-, hydrochloride (1:1); 1-Benzyl-4-piperidinecarboxylic acid HCl; NSC 405124; 1-(Phenylmethyl)piperidine-4-carboxylic acid hydrochloride; BPC Hydrochloride; 1-Bn-piperidine-4-COOH • HCl
EINECS	Contact for details

Quality Control

Our 1-Benzyl-Piperidine-4-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent product degradation or clumping. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.