Description

3-Bromo-2-Hydroxy-6-Methylbenzoic Acid is a halogenated hydroxybenzoic acid derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals developing novel active ingredients, where it is used to introduce specific bromo, hydroxy, and carboxylic acid functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory, antimicrobial, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and polymers with specific functional properties.
• Custom Synthesis and Contract Manufacturing: A crucial building block for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	3-Bromo-2-Hydroxy-6-Methylbenzoic Acid
CAS No.	681467-89-0
Molecular Formula	C8H7BrO3
Molecular Weight	231.05 g/mol
Synonyms	3-Bromo-2-hydroxy-6-methylbenzoic acid; 2-Hydroxy-3-bromo-6-methylbenzoic acid; 6-Methyl-3-bromosalicylic acid; Benzoic acid, 3-bromo-2-hydroxy-6-methyl-; 3-Bromo-6-methylsalicylic acid; 3-Bromo-2-hydroxy-p-toluic acid
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-2-Hydroxy-6-Methylbenzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications, which typically include identity confirmation (IR, NMR), purity assay (HPLC), and control of key impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We operate under a cGMP-compliant quality system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.