Description

1H-Indole-1-Acetamide, n-(4-Fluorophenyl)-3-(Hydroxymethyl)- is a high-purity, synthetically valuable indole derivative, distinguished by its fluorophenyl and hydroxymethyl functional groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research, enabling the development of novel bioactive molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for targeted synthesis programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: A versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its modifiable indole core and functional handles.
• Agrochemical Development: Building block for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Biochemical Probe Synthesis: Used in the development of molecular probes for studying enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	1H-Indole-1-Acetamide, n-(4-Fluorophenyl)-3-(Hydroxymethyl)-
CAS No.	680606-03-5
Molecular Formula	C17H15FN2O2
Molecular Weight	298.31 g/mol
Synonyms	N-(4-Fluorophenyl)-3-(hydroxymethyl)-1H-indole-1-acetamide; 3-(Hydroxymethyl)-N-(4-fluorophenyl)-1H-indole-1-acetamide; 1H-Indole-1-acetamide, N-(4-fluorophenyl)-3-(hydroxymethyl)-; 680606-03-5; 3-Hydroxymethyl-N-(4-fluorophenyl)indole-1-acetamide
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Acetamide, n-(4-Fluorophenyl)-3-(Hydroxymethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and identity confirmation, meeting the stringent requirements for research and development use. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.