Description

n-[(2,5-Dichloro-3-Pyridyl)Carbonyl]-N'-(4-Methylphenyl)Urea is a specialized organic compound belonging to the diaryl urea class, designed for high-value research and development applications. This compound serves as a critical advanced intermediate or pharmacological reference standard in the synthesis of novel active ingredients. It is primarily sought by pharmaceutical R&D and agrochemical research organizations focused on developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Research: Used as a precursor in developing novel herbicides or plant growth regulators with specific mode-of-action.
• Biochemical Tool Compound: Serves as a reference standard or probe molecule in biological target validation and assay development.
• Organic Synthesis Research: A valuable substrate for method development in cross-coupling and heterocyclic chemistry within academic and industrial labs.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials requiring specific aromatic urea structures.

Basic Information

Product Name	n-[(2,5-Dichloro-3-Pyridyl)Carbonyl]-N'-(4-Methylphenyl)Urea
CAS No.	680216-67-5
Molecular Formula	C14H11Cl2N3O2
Molecular Weight	324.16 g/mol
Synonyms	1-[(2,5-Dichloropyridin-3-yl)carbonyl]-3-(4-methylphenyl)urea; N-(2,5-Dichloropyridine-3-carbonyl)-N'-(p-tolyl)urea; Urea, N-[(2,5-dichloro-3-pyridinyl)carbonyl]-N'-(4-methylphenyl)-; 680216-67-5; 2,5-Dichloro-N-((4-methylphenyl)carbamoyl)nicotinamide; Diarylcarbonyl Urea Derivative
EINECS	Contact for details

Quality Control

Our production of n-[(2,5-Dichloro-3-Pyridyl)Carbonyl]-N'-(4-Methylphenyl)Urea adheres to stringent GMP-like guidelines for research chemicals. Every batch undergoes comprehensive analytical characterization including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure consistency and identity. A detailed Certificate of Analysis (COA) with lot-specific data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the original container sealed under inert atmosphere when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.