Description

Methyl 6-Bromo-2-Chloroquinoline-4-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive bromo and chloro substituents, which enable precise, sequential functionalization to construct complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Research: Serves as a foundational scaffold for developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its rigid, planar structure and halogen handles.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and for tagging biomolecules.
• Academic & Contract Research: A versatile starting material for methodological development in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and heterocyclic chemistry.

Basic Information

Product Name	Methyl 6-Bromo-2-Chloroquinoline-4-Carboxylate
CAS No.	680213-43-8
Molecular Formula	C11H7BrClNO2
Molecular Weight	300.54 g/mol
Synonyms	6-Bromo-2-chloroquinoline-4-carboxylic acid methyl ester; Methyl 6-bromo-2-chloro-4-quinolinecarboxylate; 2-Chloro-6-bromoquinoline-4-carboxylic acid methyl ester; Quinoline-4-carboxylic acid, 6-bromo-2-chloro-, methyl ester; 680213-43-8; Methyl 2-chloro-6-bromoquinoline-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Bromo-2-Chloroquinoline-4-Carboxylate adheres to stringent in-process controls and final batch release testing. We guarantee high chemical purity and lot-to-lot consistency suitable for demanding research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.