Description

Ethyl 4-Chloro-2-(Trifluoromethyl)Quinoline-6-Carboxylate is a high-value, multifunctional quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring both chloro and trifluoromethyl substituents, makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active ingredients, particularly for agrochemical and pharmaceutical applications where the introduction of fluorine atoms is strategically important.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for anti-infective, anti-inflammatory, and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the synthesis of functionalized quinoline-based ligands, dyes, or organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Ethyl 4-Chloro-2-(Trifluoromethyl)Quinoline-6-Carboxylate
CAS No.	680211-86-3
Molecular Formula	C₁₃H₉ClF₃NO₂
Molecular Weight	303.67 g/mol
Synonyms	Ethyl 4-chloro-2-(trifluoromethyl)-6-quinolinecarboxylate; 6-Quinolinecarboxylic acid, 4-chloro-2-(trifluoromethyl)-, ethyl ester; 4-Chloro-2-trifluoromethylquinoline-6-carboxylic acid ethyl ester; Ethyl 4-chloro-2-trifluoromethylquinoline-6-carboxylate; 680211-86-3; Quinoline-6-carboxylic acid, 4-chloro-2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-Chloro-2-(Trifluoromethyl)Quinoline-6-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.