Description

4-Chloro-3-Cyano-1,2-Dihydro-2-Oxoquinoline is a high-value, multi-functional heterocyclic building block with the CAS number 680210-85-9. This compound is a critical intermediate in the synthesis of advanced pharmaceutical compounds and agrochemicals, prized for its unique quinoline core and reactive chloro and cyano substituents. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

This versatile chemical intermediate serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the bioactive quinoline scaffold.
• Organic Synthesis & Material Science: Serves as a versatile precursor for creating complex heterocyclic compounds, dyes, and functional organic materials.
• Research & Development: Essential for medicinal chemistry programs and academic research focused on exploring new chemical entities and biological activities.

Basic Information

Product Name	4-Chloro-3-Cyano-1,2-Dihydro-2-Oxoquinoline
CAS No.	680210-85-9
Molecular Formula	C10H5ClN2O
Molecular Weight	204.61 g/mol
Synonyms	4-Chloro-3-cyano-2-hydroxyquinoline; 4-Chloro-3-cyano-2(1H)-quinolinone; 4-Chloro-2-oxo-1,2-dihydroquinoline-3-carbonitrile; 2-Hydroxy-4-chloroquinoline-3-carbonitrile; 680210-85-9; Quinoline-3-carbonitrile, 4-chloro-1,2-dihydro-2-oxo-; 4-Chloro-3-cyano-1H-quinolin-2-one
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production follows cGMP principles where applicable, and every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.