Description

1H-Pyrrolo[1,2-A]Azepine-1,5(6H)-Dione,7,8,9,9A-Tetrahydro-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a unique structural scaffold for medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new biological activities.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target APIs under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRMO): Supplied to service organizations supporting pharmaceutical companies in early-stage drug discovery and development programs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	1H-Pyrrolo[1,2-A]Azepine-1,5(6H)-Dione,7,8,9,9A-Tetrahydro-(9Ci)
CAS No.	680193-49-1
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	7,8,9,9a-Tetrahydro-1H-pyrrolo[1,2-a]azepine-1,5(6H)-dione; 1H-Pyrrolo[1,2-a]azepine-1,5(6H)-dione, 7,8,9,9a-tetrahydro-; Fused bicyclic lactam; Hexahydropyrroloazepinedione; Advanced pharmaceutical intermediate (API Intermediate); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[1,2-A]Azepine-1,5(6H)-Dione,7,8,9,9A-Tetrahydro-(9Ci) is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with batch-specific data are provided and available upon request. We support development projects requiring material produced under GMP-like controls for non-clinical and clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.