Description

Carbamic Acid, (5-Bromo-1,4,5,6-Tetrahydro-2-Pyrimidinyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized brominated pyrimidine derivative carbamate ester, serving as a high-value synthetic intermediate. This compound is crucial for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its role in nucleophilic substitution and coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides where the bromo and carbamate functionalities are essential.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Process Chemistry: Utilized in route scouting and optimization for scalable manufacturing processes of target molecules.

Basic Information

Product Name	Carbamic Acid, (5-Bromo-1,4,5,6-Tetrahydro-2-Pyrimidinyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	679430-58-1
Molecular Formula	C9H16BrN3O2
Molecular Weight	278.15 g/mol
Synonyms	tert-Butyl (5-bromo-1,4,5,6-tetrahydropyrimidin-2-yl)carbamate; 5-Bromo-1,4,5,6-tetrahydro-2-pyrimidinamine, N-BOC derivative; N-Boc-5-bromo-1,4,5,6-tetrahydropyrimidin-2-amine; (5-Bromo-1,4,5,6-tetrahydro-2-pyrimidinyl)carbamic acid tert-butyl ester; 679430-58-1; Boc-5-Bromo-THP; tert-Butyl 5-bromo-3,4-dihydro-2H-pyrimidine-1-carboxylate (tautomeric form)
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (5-Bromo-1,4,5,6-Tetrahydro-2-Pyrimidinyl)-, 1,1-Dimethylethyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.