Description

1-(Difluoromethyl)-6-Oxo-1,6-Dihydropyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoromethyl-substituted pyridone structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and other fine chemical products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting metabolic and inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the bioactivity of the difluoromethyl and pyridone moieties.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in medicinal and organic chemistry.
• Material Science: Potential applications in the research of specialty polymers and advanced materials with specific electronic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1-(Difluoromethyl)-6-Oxo-1,6-Dihydropyridine-3-Carboxylic Acid
CAS No.	677761-98-7
Molecular Formula	C7H5F2NO3
Molecular Weight	189.12 g/mol
Synonyms	1-(Difluoromethyl)-6-oxo-1,6-dihydro-3-pyridinecarboxylic acid; 6-Oxo-1-(difluoromethyl)-1,6-dihydropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 1-(difluoromethyl)-1,6-dihydro-6-oxo-; 1-(Difluoromethyl)-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid; 1-(Difluoromethyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 677761-98-7)
EINECS	Contact for details

Quality Control

Our production of 1-(Difluoromethyl)-6-Oxo-1,6-Dihydropyridine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. We offer material suitable for research and development as well as scalable grades for commercial manufacturing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.