Description

(S)-1-Cyclobutylethanamine is a chiral amine building block of significant importance in modern synthetic chemistry. Its value lies in its rigid cyclobutyl scaffold and stereochemically defined chiral center, which are crucial for imparting specific three-dimensional properties to target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly as a key intermediate in the development of chiral ligands and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule affects biological activity.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new reaction pathways in organic synthesis.
• Fine Chemical Production: Acts as a building block for manufacturing complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	(S)-1-Cyclobutylethanamine
CAS No.	677743-98-5
Molecular Formula	C6H13N
Molecular Weight	99.17 g/mol
Synonyms	(S)-1-Cyclobutylethylamine; (S)-1-Cyclobutyl-1-ethanamine; (S)-1-Cyclobutylethan-1-amine; (1S)-1-Cyclobutylethanamine; (S)-(-)-1-Cyclobutylethylamine; (S)-α-Methylcyclobutanemethylamine; (S)-Cyclobutylmethylamine, α-methyl-; (S)-1-Amino-1-cyclobutylethane
EINECS	Contact for details

Quality Control

Our (S)-1-Cyclobutylethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.