Description

5-Bromo-Benzo[D]Isothiazole-3-Carboxylic Acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, incorporating both a reactive carboxylic acid group and a halogenated benzoisothiazole scaffold, enabling its use as a versatile precursor for constructing complex molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science. The CAS number for this compound is 677304-78-8.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and inflammation.
• Agrochemical Research: Used in the synthesis of new herbicide and fungicide candidates, leveraging the bioactivity of the isothiazole moiety.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	5-Bromo-Benzo[D]Isothiazole-3-Carboxylic Acid
CAS No.	677304-78-8
Molecular Formula	C8H4BrNO2S
Molecular Weight	258.09 g/mol
Synonyms	5-Bromobenzo[d]isothiazole-3-carboxylic acid; 5-Bromo-1,2-benzisothiazole-3-carboxylic acid; 3-Carboxy-5-bromobenzo[d]isothiazole; 677304-78-8; 5-Bromo-benzo[d]isothiazole-3-carboxylic acid; 5-Bromobenzoisothiazole-3-carboxylic acid; 5-Bromo-1,2-benzisothiazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-Benzo[D]Isothiazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and organic solvents as indicated by its chemical properties. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.