Description

6,9-Methano-9H-Benzocyclohepten-9-One,1,2,3,4,4A,5,8,9A-Octahydro-,(4Ar,5S,8R,9Ar)-Rel-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex, rigid polycyclic framework, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct intricate polycyclic systems due to its defined stereochemistry and functional handle.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore novel chemical space.
• Asymmetric Catalysis Substrate: Serves as a substrate for developing and testing new asymmetric synthetic methodologies.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	6,9-Methano-9H-Benzocyclohepten-9-One,1,2,3,4,4A,5,8,9A-Octahydro-,(4Ar,5S,8R,9Ar)-Rel-(9Ci)
CAS No.	677022-11-6
Molecular Formula	C14H18O
Molecular Weight	202.29 g/mol
Synonyms	(4aR,5S,8R,9aR)-1,2,3,4,4a,5,8,9a-Octahydro-6,9-methanobenzocyclohepten-9-one; rel-(4aR,5S,8R,9aR)-1,2,3,4,4a,5,8,9a-Octahydro-6,9-methanobenzocyclohepten-9-one; 6,9-Methano-9H-benzocyclohepten-9-one, 1,2,3,4,4a,5,8,9a-octahydro-, (4aR,5S,8R,9aR)-rel-; Octahydro-6,9-methanobenzocyclohepten-9-one (stereoisomer); CAS 677022-11-6
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system adheres to cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.