Description

o-(4-Fluorobutyl)Hydroxylamine Hydrochloride is a specialized organic building block featuring a fluorinated alkyl chain and a protected hydroxylamine functionality. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for advanced synthesis. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating affinity probes and activity-based protein profiling (ABPP) reagents.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers and fluorinated materials with unique surface properties.
• Cross-coupling Reactions: The hydroxylamine hydrochloride group can be utilized in palladium-catalyzed amination and other metal-mediated transformations.

Basic Information

Product Name	o-(4-Fluorobutyl)Hydroxylamine Hydrochloride
CAS No.	676525-71-6
Molecular Formula	C₄H₁₁ClFNO
Molecular Weight	143.59 g/mol
Synonyms	4-Fluorobutylhydroxylamine hydrochloride; N-(4-Fluorobutyl)hydroxylamine hydrochloride; (4-Fluorobutoxy)amine hydrochloride; 4-Fluoro-N-hydroxybutan-1-amine hydrochloride; 1-Amino-4-fluorobutoxy hydrochloride; Hydroxylamine, N-(4-fluorobutyl)-, hydrochloride; Butyl, 4-fluoro-, hydroxylamine, hydrochloride
EINECS	Contact for details

Quality Control

Our o-(4-Fluorobutyl)Hydroxylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.