Description

o-(4,4,4-Trifluorobutyl)Hydroxylamine Hydrochloride is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of a trifluorobutyl-hydroxylamine moiety can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for modifying polymer surfaces or creating fluorinated functional materials with unique surface properties.
• Chemical Biology & Proteomics: Employed as a reagent for the selective modification of proteins or other biomolecules, useful in probe development and activity-based protein profiling.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to introduce nitrogen and fluorine functionalities simultaneously, enabling access to diverse chemical libraries for screening.

Basic Information

Product Name	o-(4,4,4-Trifluorobutyl)Hydroxylamine Hydrochloride
CAS No.	676525-70-5
Molecular Formula	C4H9F3NO • HCl
Molecular Weight	195.58 g/mol
Synonyms	O-(4,4,4-Trifluorobutyl)hydroxylamine hydrochloride; 4,4,4-Trifluoro-N-hydroxybutan-1-amine hydrochloride; N-Hydroxy-4,4,4-trifluorobutylamine hydrochloride; (4,4,4-Trifluorobutoxy)amine hydrochloride; Hydroxylamine, O-(4,4,4-trifluorobutyl)-, hydrochloride; 676525-70-5; 4,4,4-Trifluorobutylhydroxylamine HCl
EINECS	Contact for details

Quality Control

Our o-(4,4,4-Trifluorobutyl)Hydroxylamine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.