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(S)-7-Bromo-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride CAS NO 676133-24-7
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CAS No.:676133-24-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(S)-7-Bromo-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is a high-purity chiral amine building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers focused on developing central nervous system (CNS) and other therapeutic agents.
Application
- Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
- Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
- Asymmetric Synthesis: Employed as a building block for constructing enantiomerically pure molecules due to its defined (S)-configuration.
- Reference Standard: Utilized as an analytical standard for method development and quality control in API manufacturing.
- Chemical Biology Probes: Acts as a starting material for creating molecular probes to study biological targets and mechanisms.
Basic Information
| Product Name | (S)-7-Bromo-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride |
| CAS No. | 676133-24-7 |
| Molecular Formula | C10H13BrN • HCl |
| Molecular Weight | 278.58 g/mol |
| Synonyms | (1S)-7-Bromo-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride; (S)-7-Bromo-1,2,3,4-tetrahydro-1-naphthylamine hydrochloride; (S)-1-Amino-7-bromo-1,2,3,4-tetrahydronaphthalene hydrochloride; (S)-7-Bromo-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride; 7-Bromo-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride, (S)-; (S)-7-Bromo-1,2,3,4-tetrahydro-naphthalen-1-ylamine HCl; (S)-7-Br-Tetralin-1-amine HCl |
| EINECS | Contact for details |
Quality Control
Our (S)-7-Bromo-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is available for every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Assay (HPLC) | ≥98.0% |
| Chiral Purity (HPLC) | ≥99.0% ee |
| Water Content (KF) | ≤1.0% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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