Description

6-(Trifluoromethoxy) Quinolin-2(1H)-One is a high-value, fluorinated quinolinone derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethoxy group imparts unique metabolic stability and lipophilicity. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for the research and production of new chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinolinone core.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as OLEDs and semiconductors, due to its conjugated structure.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a fluorescent tag or probe precursor.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	6-(Trifluoromethoxy) Quinolin-2(1H)-One
CAS No.	676131-27-4
Molecular Formula	C₁₀H₆F₃NO₂
Molecular Weight	229.16 g/mol
Synonyms	6-(Trifluoromethoxy)-1H-quinolin-2-one; 2-Hydroxy-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)quinolin-2-ol; 6-Trifluoromethoxy-2-quinolinone; 6-Trifluoromethoxy-2(1H)-quinolinone; Quinolin-2(1H)-one, 6-(trifluoromethoxy)-; 676131-27-4
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethoxy) Quinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.