Description

8-Chloro-4,4-Dimethyl-1,3-Dihydroquinolin-2-One is a high-purity, synthetically valuable quinolinone derivative. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis: Versatile precursor for constructing complex heterocyclic frameworks and functionalized quinolines.
• Material Science: Research component for developing organic semiconductors, ligands for metal complexes, and specialty polymers.
• Biochemical Tool: Potential use in biochemical assays and as a probe for studying enzyme inhibition.
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery research in university and CRO laboratories.

Basic Information

Product Name	8-Chloro-4,4-Dimethyl-1,3-Dihydroquinolin-2-One
CAS No.	676116-21-5
Molecular Formula	C11H12ClNO
Molecular Weight	209.67 g/mol
Synonyms	8-Chloro-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-2-one; 8-Chloro-4,4-dimethyl-2-quinolinone; 8-Chloro-4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one; 8-Chloro-4,4-dimethyl-1,3-dihydro-2H-quinolin-2-one; 2(1H)-Quinolinone, 8-chloro-4,4-dimethyl-1,3-dihydro-; 676116-21-5; 8-Chloro-4,4-dimethylquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 8-Chloro-4,4-Dimethyl-1,3-Dihydroquinolin-2-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.