Description

2,3,5-Trifluoropyridine-4-Carboxylic Acid, 97 is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its ability to introduce both a carboxylic acid handle and multiple fluorine atoms into target molecules, significantly modulating their physicochemical and biological properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to impart specific dielectric and surface properties.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,3,5-Trifluoropyridine-4-Carboxylic Acid, 97
CAS No.	675602-91-2
Molecular Formula	C6H2F3NO2
Molecular Weight	177.08 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2,3,5-trifluoro-; 2,3,5-Trifluoropyridine-4-carboxylic acid; 2,3,5-Trifluoroisonicotinic acid; 2,3,5-Trifluoro-4-pyridinecarboxylic acid; 4-Carboxy-2,3,5-trifluoropyridine; Trifluoropyridinecarboxylic acid; TFPC Acid
EINECS	Contact for details

Quality Control

Our 2,3,5-Trifluoropyridine-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the specified 97% minimum purity. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.