Description

2H-Pyrido[1,2-A]Pyrimidine-7,8,9-Triol, 3,4,6,7,8,9-Hexahydro-6-(Hydroxymethyl)-, (6R,7R,8S,9R)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering researchers and manufacturers precise control over final product structure and activity. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in developing novel therapeutics, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Synthesis of Complex Heterocycles: Serves as a versatile precursor for constructing fused polycyclic systems with potential biological activity.
• Biochemical Tool Compound: May be utilized in the development of enzyme inhibitors or receptor modulators for research purposes.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential commercial drug manufacturing.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrimidine-7,8,9-Triol, 3,4,6,7,8,9-Hexahydro-6-(Hydroxymethyl)-, (6R,7R,8S,9R)- (9Ci)
CAS No.	675130-39-9
Molecular Formula	C9H13NO5
Molecular Weight	215.20 g/mol
Synonyms	(6R,7R,8S,9R)-6-(Hydroxymethyl)-3,4,6,7,8,9-hexahydro-2H-pyrido[1,2-a]pyrimidine-7,8,9-triol; 2H-Pyrido[1,2-a]pyrimidine-7,8,9-triol, 3,4,6,7,8,9-hexahydro-6-(hydroxymethyl)-, (6R,7R,8S,9R)-; CAS 675130-39-9; (6R,7R,8S,9R)-Hexahydro-6-(hydroxymethyl)-2H-pyrido[1,2-a]pyrimidine-7,8,9-triol; A stereoisomer of a polyhydroxylated pyridopyrimidine.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to verify identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can adhere to cGMP guidelines for pharmaceutical applications as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.