Description

6'-Amino-3'-butyl-5-fluoro-1,1',3,4'-tetrahydro-2-oxospiro(2H-indole-3,4'-pyrano[2,3-c]pyrazole)-5'-carbonitrile is a high-purity, complex heterocyclic organic compound featuring a unique spirocyclic core structure. This compound is of significant commercial interest as a key synthetic intermediate and a versatile scaffold for advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D organizations for the discovery and synthesis of novel active ingredients. Its specific molecular architecture makes it a valuable building block for creating compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic framework for bioactivity.
• Chemical Biology Probe: Acts as a specialized scaffold for designing molecular probes to study enzyme function and protein-ligand interactions in biological systems.
• Material Science Research: Investigated for its potential in creating advanced organic materials due to its complex, rigid molecular structure.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects and library synthesis.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	6'-Amino-3'-butyl-5-fluoro-1,1',3,4'-tetrahydro-2-oxospiro(2H-indole-3,4'-pyrano[2,3-c]pyrazole)-5'-carbonitrile
CAS No.	674807-59-1
Molecular Formula	C19H20FN5O2
Molecular Weight	369.40 g/mol
Synonyms	6'-Amino-3'-butyl-5-fluoro-1,1',3,4'-tetrahydro-2-oxospiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile; Spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile, 6'-amino-3'-butyl-5-fluoro-1,1',3,4'-tetrahydro-2-oxo-; 6-Amino-3-butyl-5-fluoro-1,3,4,9-tetrahydro-2-oxospiro[2H-indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile; 674807-59-1; AKOS025247324; CTK8G0182; ZINC000103074557; FCH674807591.
EINECS	Contact for details

Quality Control

Our production of 6'-Amino-3'-butyl-5-fluoro-1,1',3,4'-tetrahydro-2-oxospiro(2H-indole-3,4'-pyrano[2,3-c]pyrazole)-5'-carbonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with client specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.