Description

6'-Amino-3'-Butyl-5-Chloro-1,1',3,4'-Tetrahydro-2-Oxospiro(2H-Indole-3,4'-Pyrano[2,3-C]Pyrazole)-5'-Carbonitrile is a complex, high-value spirocyclic heterocyclic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate molecular architecture, featuring fused indole, pyran, and pyrazole rings, makes it a versatile scaffold for constructing novel bioactive molecules. This compound is primarily sought after by medicinal chemists and R&D departments in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule therapeutics targeting a range of diseases.
• Medicinal Chemistry Research: Used as a core scaffold in hit-to-lead and lead optimization programs to explore new chemical space and structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines for global clients.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6'-Amino-3'-Butyl-5-Chloro-1,1',3,4'-Tetrahydro-2-Oxospiro(2H-Indole-3,4'-Pyrano[2,3-C]Pyrazole)-5'-Carbonitrile
CAS No.	674807-36-4
Molecular Formula	C19H20ClN5O2
Molecular Weight	385.85 g/mol
Synonyms	6'-Amino-3'-butyl-5-chloro-1,1',3,4'-tetrahydro-2-oxospiro[2H-indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile; 5-Chloro-6'-amino-3'-butyl-1,1',3,4'-tetrahydro-2-oxospiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile; Spiro[indole-3,4'-pyrano[2,3-c]pyrazole] derivative; CAS 674807-36-4; 6'-Amino-3'-butyl-5-chloro-1,1',3,4'-tetrahydro-2-oxospiro(2H-indole-3,4'-pyrano[2,3-c]pyrazole)-5'-carbonitrile; 1,1',3,4'-Tetrahydro-2-oxospiro(2H-indole-3,4'-pyrano[2,3-c]pyrazole)-5'-carbonitrile, 6'-amino-3'-butyl-5-chloro-
EINECS	Contact for details

Quality Control

Our 6'-Amino-3'-Butyl-5-Chloro-1,1',3,4'-Tetrahydro-2-Oxospiro(2H-Indole-3,4'-Pyrano[2,3-C]Pyrazole)-5'-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.