Description

4-Boc-4,7-Diazaspiro[2.5]Octane is a high-value, protected spirocyclic diamine building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the exploration of novel three-dimensional chemical space. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical industry for creating new drug candidates, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting complex biological pathways.
• Medicinal Chemistry: Used in hit-to-lead and lead optimization campaigns to introduce constrained, spirocyclic motifs that can improve potency, selectivity, and metabolic stability of drug candidates.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides where the spirocyclic structure can confer unique biological activity.
• Chemical Biology: Serves as a scaffold for constructing molecular probes and tools to study enzyme function and protein-protein interactions.
• Process Chemistry: Used in the development of scalable synthetic routes for the commercial production of advanced intermediates.
• Library Synthesis: A valuable reagent for generating diverse compound libraries in high-throughput screening for drug discovery.

Basic Information

Product Name	4-Boc-4,7-Diazaspiro[2.5]Octane
CAS No.	674792-08-6
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl 4,7-diazaspiro[2.5]octane-4-carboxylate; 4-(tert-Butoxycarbonyl)-4,7-diazaspiro[2.5]octane; 4,7-Diazaspiro[2.5]octane-4-carboxylic acid, 1,1-dimethylethyl ester; 4-Boc-4,7-diaza-spiro[2.5]octane; 4-N-Boc-4,7-diazaspiro[2.5]octane; Boc-Protected 4,7-Diazaspiro[2.5]octane; 4,7-Diazaspiro[2.5]octane, N-Boc-protected
EINECS	Contact for details

Quality Control

Our 4-Boc-4,7-Diazaspiro[2.5]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.