Description

tert-Butyl 7-Benzyl-4,7-Diazaspiro[2.5]Octane-4-Carboxylate is a high-value, spirocyclic organic building block featuring a protected diazaspiro[2.5]octane core. This compound is a critical synthetic intermediate for medicinal chemistry research and pharmaceutical development, prized for its unique three-dimensional structure that can enhance drug-like properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel bioactive molecules, particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Employed in the creation of tool compounds to study biological pathways and enzyme functions.
• Agrochemical Research: Investigated as an intermediate for novel active ingredients with potential pesticidal or herbicidal activity.
• Academic Synthesis: Used in advanced organic chemistry laboratories for methodology development and the study of spirocyclic compound properties.

Basic Information

Product Name	tert-Butyl 7-Benzyl-4,7-Diazaspiro[2.5]Octane-4-Carboxylate
CAS No.	674792-03-1
Molecular Formula	C18H26N2O2
Molecular Weight	302.41 g/mol
Synonyms	4-Boc-7-benzyl-4,7-diazaspiro[2.5]octane; tert-Butyl 7-benzyl-4,7-diazaspiro[2.5]octane-4-carboxylate; 7-Benzyl-4-(tert-butoxycarbonyl)-4,7-diazaspiro[2.5]octane; 4,7-Diazaspiro[2.5]octane-4-carboxylic acid, 7-(phenylmethyl)-, 1,1-dimethylethyl ester; Boc-4,7-diazaspiro[2.5]octane-7-benzyl; 1-Boc-4-benzyl-1,4-diazaspiro[2.5]octane
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Benzyl-4,7-Diazaspiro[2.5]Octane-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring material traceability and reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.