Description

trans-4-Ethoxycyclohexanamine Hcl CAS NO 674367-29-4 is a high-purity organic building block featuring a functionalized cyclohexylamine core. This compound is valued for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily utilized by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and specialty polymers.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry programs.
• Peptidomimetics: The amine functionality allows for incorporation into peptide backbones to create novel bioactive compounds.

Basic Information

Product Name	trans-4-Ethoxycyclohexanamine Hcl
CAS No.	674367-29-4
Molecular Formula	C8H18ClNO
Molecular Weight	179.69 g/mol
Synonyms	trans-4-Ethoxycyclohexanamine hydrochloride; (1r,4r)-4-Ethoxycyclohexanamine hydrochloride; 4-Ethoxycyclohexanamine hydrochloride (trans-); Cyclohexanamine, 4-ethoxy-, hydrochloride, (1R,4R)-; 4-Ethoxycyclohexylamine hydrochloride; trans-4-Ethoxy-1-aminocyclohexane hydrochloride; 1-Amino-4-ethoxycyclohexane hydrochloride; 4-Aethoxy-cyclohexylamin-hydrochlorid
EINECS	Contact for details

Quality Control

Our trans-4-Ethoxycyclohexanamine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent analysis. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.