Description

Pyrrolo[1,2-A]Pyrimidin-8-Ol, 2,3,4,6,7,8-Hexahydro-, (8S)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This molecule serves as a sophisticated chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing complex molecular libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-up: Serves as a key intermediate in the optimization and commercial-scale synthesis of target drug candidates.
• Asymmetric Synthesis: Leverages its defined (8S) stereochemistry as a chiral auxiliary or template in enantioselective synthetic routes.
• Fine Chemical Production: Employed in the manufacture of specialized, high-value chemicals for agrochemical and material science applications.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology research.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrimidin-8-Ol, 2,3,4,6,7,8-Hexahydro-, (8S)- (9Ci)
CAS No.	674303-47-0
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	(8S)-2,3,4,6,7,8-Hexahydropyrrolo[1,2-a]pyrimidin-8-ol; (8S)-Octahydropyrrolo[1,2-a]pyrimidin-8-ol; Pyrrolo[1,2-a]pyrimidin-8-ol, 2,3,4,6,7,8-hexahydro-, (8S)-; (8S)-Hexahydropyrrolo[1,2-a]pyrimidin-8-ol; CAS 674303-47-0
EINECS	Contact for details

Quality Control

Every batch of Pyrrolo[1,2-A]Pyrimidin-8-Ol, 2,3,4,6,7,8-Hexahydro-, (8S)- (9Ci) is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material is characterized by HPLC, NMR, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.